scleroderma

Tissue culture and enzyme studies indicate increased fibroblastie activity and collagen production during the active state of scleroderma 5 6. Connective tissue is widespread.


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Among them is collagen of the skin.

. Scleroderma is an autoimmune connective tissue and rheumatic disease that causes inflammation in the skin and other areas of the body. Systemic sclerosis is also called scleroderma progressive systemic sclerosis or CREST syndrome. Some people develop violet-colored skin which means that the scleroderma is active and expanding.

Scleroderma causes extremely dry skin and dry skin itches. In patients with scleroderma the immune system triggers other cells to produce too much collagen a protein. Calcinosis Raynauds phenomenon esophageal.

Scleroderma is an autoimmune rheumatic and chronic disease that affects the body by hardening connective tissue. Scleroderma is a long-lasting disease that affects your skin connective tissue and internal organs. Scleroderma probably is both a vascular disease and an autoimmune disorder 4.

Scleroderma literally means hard skin. While there is no cure for scleroderma a variety of treatments can ease symptoms and improve quality of life. It adds strength to organs and other parts of the body Connective tissue is made of many kinds of proteins.

Scleroderma or systemic sclerosis is a chronic connective tissue disease generally classified as one of the autoimmune rheumatic diseases. However the relative proportions of Type I and Type III collagen appear similar to those of normal adult dermis 7. Normally the immune system helps defend the body against disease and infection.

Skin color changes The patches of hardened skin can be lighter or darker than your natural skin color. The extreme dryness can cause the skin to breakdown and sores can form. Symptoms may include areas of thickened skin stiffness feeling tired and poor blood flow to the fingers or toes with cold exposure.

Scleroderma sklair-oh-DUR-muh is a group of rare diseases that involve the hardening and tightening of the skin and connective tissues. The word scleroderma comes from the Greek word sclero meaning hard and the Latin word derma meaning skin. This inflammation leads to patches of tight hard skin.

A connective tissue disease is one that affects tissues such as skin tendons and cartilage. The disease can be either localized to the skin or involve other organs as well. Scleroderma involves many systems in your body.

Scleroderma affects women more often than men and most commonly occurs between the ages of 30 and 50. Scleroderma is a chronic although rare autoimmune disease in which normal tissue is replaced with dense thick fibrous tissue. It happens when your immune system causes your body to make too much of the protein collagen.

Scleroderma is a group of autoimmune diseases that may result in changes to the skin blood vessels muscles and internal organs.


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